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2018 Vol.30, Issue 1 Preview Page

Research Article

Improvement of Lipid Metabolism of Inonotus obliquus and roasted Inonotus obliquus extracts in mice a fed high-fat diet

고지방 식이 마우스에서 로스팅 유무에 따른 차가버섯의 지질대사 개선 효과

N. E. Kim1
,
M. O. Lee1
,
M. H. Jang1
,
B. H. Chung1*
김 나은1
,
이 미옥1
,
장 미희1
,
정 병희1*
1Research and Development Institute, Haesong KNS
1(주)해송KNS 기업부설연구소
*교신저자. *Corresponding Author. 
March 2018. pp. 31-40
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Abstract

This study was conducted to investigate the effects of Inonotus obliquus and roasted Inonotus obliquus extract powder on lipid metabolism in C57BL/6J mice fed a high-fat diet (HFD). Mice were randomly divided into five groups: normal diet (ND) group, HFD group, HFD group with 1% Inonotus obliquus extract powder (HFD-I) group, HFD with roasted Inonotus obliquus extract powder condition 1 diet (HFD-RI1) group, and HFD with roasted Inonotus obliquus extract powder condition 2 diet (HFD-RI2) group. After 10 weeks, the HFD-I, HFD-RI1, and HFD-RI2 groups had a significantly reduced epididymal adipose tissue weight. Plasma triglyceride, total cholesterol, and low-density lipoprotein-cholesterol levels were significantly decreased in the HFD group compared to those of the ND group. Furthermore, the atherogenic index and cardiac risk factor were suppressed in the HFD-I, HFD-RI1, and HFD-RI2 groups, with a significant decrease detected in the HFD-RI1 group compared to the HFD group. These results suggest that roasted Inonotus obliquus extract powder may be an effective anti-obesity material by reducing plasma triglyceride and cholesterol levels.

Keywords
Anti-obesity
C57BL/6J mouse
Inonotus obliquus
Lipid metabolism
Roasting

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Information
  • Publisher :Agriculture and Life Sciences Research Institute, Kangwon National University
  • Publisher(Ko) :강원대학교 농업생명과학대학 농업생명과학연구원
  • Journal Title :Journal of Agricultural, Life and Environmental Sciences
  • Journal Title(Ko) :농업생명환경연구
  • Volume : 30
  • No :1
  • Pages :31-40
  • Received Date : 2017-12-01
  • Revised Date : 2018-02-01
  • Accepted Date : 2018-02-05
  • DOI :https://doi.org/10.12972/jales.20180003
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